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我国科学家发现了可抑制HIV扩散的蛋白质

来源:365体育官网点击:时间:2019-04-15 13:40

Chinese scientists have identified a new protein that restricts HIV infection, which could pave way for development of new antivirus drugs.

我国科学家已经发现了一种新的可抑制HIV感染的蛋白质,此发现将为新的抗病毒药物的研发奠定基础。

The protein, P-selectin glycoprotein ligand 1 (PSGL-1), can inhibit HIV reverse transcription and effectively block its viral infectivity, according to the research, published on science journal Nature earlier this month.

本月早些时候发表在科学杂志《自然》(Nature)上的一项研究表明,这种名为p-选择素糖蛋白配体1 (PSGL-1)的蛋白质能够抑制HIV的逆转录,并有效地阻止其病毒感染。

我国科学家发现了可抑制HIV扩散的蛋白质.png

The study, conducted by researchers from universities including Tsinghua University in Beijing, and Fudan University in Shanghai, also showed PSGL-1 can be down regulated by HIV-1 Vpu, an accessory protein of HIV, so it fails to resist HIV infection.

北京清华大学和上海复旦大学研究人员组成的研究小组所发表的研究也表明,HIV的附属蛋白HIV-1 Vpu对PSGL-1有向下调节作用,所以它未能阻止HIV的传染。

Further research is underway to develop a drug that can inhibit the HIV protein so PSGL-1 can work to resist HIV.

能够抑制HIV蛋白的药物研究正在进一步开展,以便PSGL-1能够运作起来对抗HIV。

来源:可可英语

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